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Dr. Michael Jaff is the Director of the Vascular Center at Massachusetts General Hospital in Boston, MA, which is a large collaborative program encompassing over 100 doctors who diagnose and treat patients with different forms of peripheral vascular disease (PVD). Our conversation with Dr. Jaff focused on peripheral arterial disease (PAD), which affects approximately 10-12 million Americans a year, and it is a common complication of diabetes that can have serious side effects, particularly amputation. We were amazed to hear that in individuals who have both diabetes and PAD, there is a threefold increased risk of dying from any cause over the next five years, not just from cardiovascular disease. This point highlights the need to treat diabetes as early as possible before complications appear because as Dr. Jaff said, it is "a bad marker of things to come."